Movement of Stem Cells

Scientists from Newcastle University have shown that human embryonic stem cells move by travelling back and forth in a line, much like ...

Scientists from Newcastle University have shown that human embryonic stem cells move by travelling back and forth in a line, much like ants moving along their trails.

Read more at: https://phys.org/news/2018-06-stem-cells.html#jCp

 Scientists from Newcastle University have shown that human embryonic stem cells move by travelling back and forth in a line, much like ants moving along their trails.
Human stem cells are at the forefront of modern molecular biology research due to their ability to give rise to any specialist human cell type, a property known as pluripotency.

However, stem cells are notoriously hard to grow in culture so to improve this, a team of mathematicians and stem cells biologists are developing mathematical models of stem cell behaviour, from a single or a few cells up to colonies of thousands.

The research published today in Physical Biology sheds important light on how stem cells interact with each other and their environment.

"At first glance cells appeared to move around aimlessly, but with closer scrutiny subtle patterns became evident," said mathematician and Postgraduate student, Laura Wadkin, who worked alongside postdoctoral researcher Dr. Sirio Orozco and academics from the Institute of Genetic Medicine to make the discovery.

"On their own, the cells were seen to shuffle along an almost straight line, often retracing their steps like ants along ant trails.

"When in pairs, the stem cells would each wander around but stay within reach of one another. In fact, we saw that they were often tethered to each other with a narrow link of cytoplasm, a bit like holding hands."

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://phys.org/news/2018-06-stem-cells.html#jCp

Scientists from Newcastle University have shown that human embryonic stem cells move by travelling back and forth in a line, much like ants moving along their trails.

Read more at: https://phys.org/news/2018-06-stem-cells.html#jCp