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Atomic Force Microscopy determines Variations in DNA Double Helix

DNA DOUBLE HELIX Researchers of the National Physical Laboratory (NPL) in collaborating with the London Centre for Nanotechnology (LCN)...

DNA DOUBLE HELIX

Researchers of the National Physical Laboratory (NPL) in collaborating with the London Centre for Nanotechnology (LCN) have tested the DNA measurements using atomic force microscopy. The team of researchers shocked at the results as they found significant changes in the double helix from the previously reported structures.
 
The researchers used AFM on a single DNA molecule at a time and have found sufficient agreements with Watson and crick's DNA model. However, in grooves depth of DNA molecule, the singe molecule image results were shocking as it showed significant variations from the original model.

 
The results were shocking because DNA grooves as the places thought to be molecular keys for protein expression of genes.
The information from the results of the research is thought to be an important outcome in DNA structure history as it'll pave a way for accurate structure measurement of DNA. This can further help in determining the method used by DNA for storing and functioning of genetic information inside its compact structure.

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